New top 5 CoViD symptoms, (23rd June)
https://covid.joinzoe.com/post/new-top-5-covid-symptoms
https://covid.joinzoe.com/post/risk-covid-after-vaccine
After 2 vaccines
fewer symptoms were reported over a shorter period of time
Headache
Runny nose
Sneezing
Sore throat
Others
Persistent cough, 8th
Anosmia, 11th
Fever, 12th
Shortness of breath, 29th
Doubly vaccinated should get tested if they have features
After 1 vaccine dose
Headache
Runny nose
Sore throat
Sneezing
Persistent cough
If unvaccinated
Headache
Sore throat
Runny nose
Fever
Persistent cough
Anosmia, 9th
Shortness of breath, 30th
indicating the symptoms as recorded previously are changing with the evolving variants of the virus
Ivermectin to be investigated in adults aged 18+
https://www.principletrial.org
https://www.principletrial.org/news/ivermectin-to-be-investigated-as-a-possible-treatment-for-covid-19-in-oxford2019s-principle-trial
University of Oxford
Investigating treatments for people at more risk of serious illness from COVID-19
N = 5,106 so far
Ivermectin is a safe, broad spectrum antiparasitic drug which is in wide use globally to treat parasitic infections.
Known antiviral properties
Small pilot studies show that early administration with ivermectin can reduce viral load and the duration of symptoms in some patients with mild COVID-19.
Professor Chris Butler
Nuffield Department of Primary Care Health Sciences
Joint Chief Investigator
Ivermectin is readily available globally,
has been in wide use for many other infectious conditions so it’s a well-known medicine with a good safety profile,
and because of the early promising results in some studies it is already being widely used to treat COVID-19 in several countries.
By including ivermectin in a large-scale trial like PRINCIPLE, we hope to generate robust evidence to determine how effective the treatment is against COVID-19,
and whether there are benefits or harms associated with its use
Treatment group
Three-day course of oral ivermectin
Control group
Standard NHS care
The trial is supported by a vast network of health and care professionals in care homes, pharmacies, NHS 111 Hubs, hospitals and more than 1400 GP practices across England, Wales, Scotland and Northern Ireland.
Source
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