All shops can reopen

Hairdressers, beauty salons, other close-contact services can open

Restaurants and pubs, food and alcohol outdoors

Gyms, spas, zoos, theme parks, libraries, community centres

Members of the same household can take a holiday in England in self-contained accommodation

Up to 15 people can attend weddings and 30 can attend funerals

Children can attend any indoor children’s activity

Care home visitors will increase to two per resident

Driving lessons can resume, with tests restarting 22 April.

UK

https://coronavirus.data.gov.uk

Cases, + 1,730 (+ 18,403)

Down 30.2%

Deaths + 7 (+ 251) = 127,087

Up 2.4%

Deaths, + 799 (7 days) = 149,968

Hospitalisations

Daily, + 221 = 2,862

Last 7 days, 1,606

Down 21%

Vaccinations

Saturday boosters, 475,230
Saturday primers, 111,109

Primer, 32,121,353 (61%)
Booster, 7,466,540

US VOVs.

Cases and deaths

https://covid.cdc.gov/covid-data-tracker/#trends_dailytrendscases

https://www.cdc.gov/coronavirus/2019-ncov/transmission/variant-cases.html

https://www.washingtonpost.com/nation/2021/04/09/coronavirus-covid-live-updates-us/

VOC increases in Michigan, 1,503 in March to 7,226 last week

https://www.worldometers.info/coronavirus/usa/michigan/

B.1.1.7 variant has become the dominant strain, present in 50 states

P.1 (Brazil) variant second, largest number in Massachusetts, Illinois and Florida

Cape Cod, Brazilian connections

US Vaccinations

119,242,902 (35.9%)

72,630,892 (21.9%)

Brazil

P.1

P.2

Projected deaths

https://covid19.healthdata.org/brazil?view=total-deaths&tab=trend

President Jair Bolsonaro

https://www.bbc.co.uk/news/world-latin-america-56663217

just a little flu

stop whining

Said he wouldn’t get vaccinated
Dismissed opportunities to purchase millions of vaccine doses

Chinese vaccines

https://www.washingtonpost.com/world/asia_pacific/china-vaccine-efficacy-not-high-gao/2021/04/11/dafe3ab6-9a8f-11eb-8f0a-3384cf4fb399_story.html

Chinese Center for Disease Control and Prevention, George Gao

China, formally considering vaccine options

To solve the problem that the efficacy of the existing vaccines is not high

Sinopharm and Sinovac, inactivated viruses

60 countries have approved Chinese vaccines

Indonesia, Pakistan, Brazil, Egypt, Turkey, United Arab Emirates, Cambodia

John and Tim write up

https://covid.joinzoe.com/blog

Source

The post England, Step two opening appeared first on Alternative.Media.

https://www.cdc.gov/media/releases/2021/s0413-JJ-vaccine.html

https://www.washingtonpost.com/health/2021/04/13/johnson-and-johnson-vaccine-blood-clots/

Cerebral venous sinus thrombosis, together with low platelets

Some sort of immune response

6 cases from 6.8 million doses

Look out for, severe headache, abdominal pain, leg pain or shortness of breath within three weeks of vaccination

Paul A.Offit, vaccine specialist, Children’s Hospital of Philadelphia

I think it’s the prudent thing to do

I think it’s real — this is a rare, but real association

Advisory Committee on Immunization Practices (ACIP), meets today

EMA also investigating, delaying European rollout

Janet Woodcock, acting commissioner, Food and Drug Administration

One reason for the pause, health professionals must know not to use heparin

All six cases in the US, occurred among women, 18 to 48

6 – 13 days after vaccination

Of the 6, 1 death and 1 critical

Of the 6, 2 discharged

The person in critical condition was (reportedly) treated with heparin

Peter Marks, director of the FDA’s centre for biologics evaluation and research

hesitate to call it a class effect related to adenovirus vector vaccines

It’s plainly obvious to us already that what we’re seeing with the Jansen vaccines looks very similar to what is being seen with the AstraZeneca vaccine

AstraZeneca, chimpanzee adenoviral vector

Janssen, human adenoviral vector vaccine

I can’t make some broad statement yet, but obviously they are from the same general class of viral vectors

Scale of the problem

100 million doses to US end of May

can produce 1 billion doses globally by the end of the year

has agreed to sell 500 million doses to developing nations via Covax purchasing agreement

agreed to sell up to 400 million to African countries

Turkey

https://www.telegraph.co.uk/global-health/science-and-disease/coronavirus-news-lockdown-pubs-restaurants-shops-cases-deaths/

Cases, + 59,187 = 3,962,000 million

Deaths, + 273 = 34,455

President Tayyip Erdogan, partial closures

Ramadan started yesterday

France

Cases, + 39,113 = 5,100,000

Deaths, + 324 (in hospital) = 99,480

ITU = 5,952

One month lockdown in place since the end of March

France will suspend all flights to and from Brazil

Sweden

AZ, being given to over 65s

J&J arriving this week

Russia

Manufacturing of Sputnik V, soon in India, (50 m per month) Serbia, Iran, Italy

India

India approved Sputnik V on Monday

UK

https://www.telegraph.co.uk/global-health/science-and-disease/lockdown-eases-worried-should-londons-cluster-south-african/

Surge PCR testing south London

Lambeth and Wandsworth (population 656,000)

Testing available for all, symptomatic or asymptomatic

Live, work or travel through

South Africa variant

Eeek, E484K, seems to reduce AZ efficacy

Still protects against severe disease

Does not seem to out compete UK variant

New formulation of AZ for third shot later this year

Who are these guys?

Vitamin D

https://vdmeta.com

Source

The post US pause Janssen vaccine appeared first on Alternative.Media.

Department of Pathology and Molecular Medicine, Queen’s University, Kingston, ON, Canada

https://ashpublications.org/blood/article/109/7/2832/125650/Adenovirus-induced-thrombocytopenia-the-role-of

Thrombocytopenia has been consistently reported following the administration of adenoviral gene transfer vectors

Adenovirus-induced thrombocytopenia is a potentially serious complication of gene therapy protocols using this type of vector.

Understanding its mechanism may help the development of measures to prevent this adverse event.

In this report, we have studied platelet-adenovirus interactions in vitro and in vivo after intravenous administration of adenovirus to mice.

We show that adenovirus induces platelet activation and promotes the formation of platelet-leukocyte aggregates both in vitro and in vivo.

Thrombocytopenia occurs between 5 and 24 hours following intravenous administration of adenovirus to mice

Adenovirus activates platelets and induces rapid exposure of P-selectin

Adenovirus activates endothelial cells

Incorrect injection technique

https://nyheder.tv2.dk/samfund/2021-03-22-ssi-anbefaler-ny-vaccineteknik-efter-sjaeldne-blodpropper

Vaccine technique can be a rare cause of clots

https://translate.google.com/translate?sl=da&tl=en&u=https://nyheder.tv2.dk/samfund/2021-03-22-ssi-anbefaler-ny-vaccineteknik-efter-sjaeldne-blodpropper

State Serum Institute of Denmark, now recommends injection aspiration before injecting vaccine

There is suspicion as to whether accidental injection of the vaccine into a blood vessel could play a role

Intravascular administration may lead to a systemic inflammatory reaction leading to blood clots

Danish nursing council

Covid-19 vaccines should be given with aspiration before injection

https://sqd34kucpgoufz3qiuiswlotka–dsr-dk.translate.goog/politik-og-nyheder/nyhed/covid-19-vacciner-skal-gives-med-aspiration-foer-injektion

Aspiration is recommended for all approved covid-19 vaccines

Consistent with the Danish Health and Medicines Authority’s guidelines

Vaccination personnel should ensure that they are injected correctly into a muscle and not into the bloodstream

Possible connection between the AstraZeneca vaccine and rare but serious side effects with blood clots and bleeding

And the link to the updated instructions from the Danish Serum Institute

https://www.ssi.dk/vaccinationer/injektionsteknik/intramuskulaer-injektion-beorn-og-voksne

Google Translate:

https://translate.google.com/translate?sl=da&tl=en&u=https://www.ssi.dk/vaccinationer/injektionsteknik/intramuskulaer-injektion-beorn-og-voksne

Danish Nurse association

https://dsr.dk/politik-og-nyheder/nyhed/covid-19-vacciner-skal-gives-med-aspiration-foer-injektion

Google Translate:

https://translate.google.com/translate?sl=da&tl=en&u=https://dsr.dk/politik-og-nyheder/nyhed/covid-19-vacciner-skal-gives-med-aspiration-foer-injektion

https://sundhedspolitisktidsskrift.dk/nyheder/4614-myndighed-sadler-om-aendrer-anbefaling-om-vaccineteknik-efter-meldinger-om-farlige-bivirkninger.html

https://translate.google.com/translate?hl=&sl=da&tl=en&u=https%3A%2F%2Fsundhedspolitisktidsskrift.dk%2Fnyheder%2F4614-myndighed-sadler-om-aendrer-anbefaling-om-vaccineteknik-efter-meldinger-om-farlige-bivirkninger.html

When vaccinating, it is important to make sure that the vaccine does not go directly into the bloodstream.

UK and WHO guidelines

https://www.gov.uk/government/collections/immunisation-against-infectious-disease-the-green-book

https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/147915/Green-Book-Chapter-4.pdf

Vaccines should not be given intravenously.

It is not necessary to aspirate the syringe after the needle is introduced into the muscle (WHO, 2004; Plotkin and Orenstein, 2004).

Plotkin SA and Orenstein WA (eds) (2008) Vaccines, 5th edition. Philadelphia: WB Saunders Company.

World Health Organization (2004) Immunization in practice: a guide for health workers. WHO.

https://apps.who.int/iris/bitstream/handle/10665/193412/9789241549097_eng.pdf?sequence=1&isAllowed=y

Tim Spector

Who are these guys?

Vitamin D

https://vdmeta.com

Source

The post Aspirate to vaccinate! appeared first on Alternative.Media.

https://www.bbc.co.uk/news/uk-politics-56800305

PM cancels India trip

Cases, + 200,000 for past 4 days

Deaths, + 1,620

Delhi lockdown for 1 week

(Weekend curfew judged ineffective)

Health services overwhelmed

Public Health England, 73 in England, 4 in Scotland

Not on red list

Chief Medical Advisor for NHS Test and Trace, Dr Susan Hopkins

UK did not have enough data yet to determine if India should be put on the list

UK Health Security Agency, please intervene now!

Not been classed as a “variant of concern”

Details on India

https://static1.squarespace.com/static/5ef3652ab722df11fcb2ba5d/t/6076f57d3b43fb2db4a7c9c9/1618408831746/India+TF+Policy+Brief+April+2021.pdf

Test positivity rates

Start of April, 2.8%

April 10th, 10.3%

Case fatality rate from March 2020 = 1.3%

Now, 0.87%

New Zealand and Australia, travel bubble

https://www.washingtonpost.com/world/asia_pacific/new-zealand-australia-travel-bubble-coronavirus/2021/04/19/d7b9dab4-a0ba-11eb-a774-7b47ceb36ee8_story.html

Monday, first quarantine-free flight from Australia to NZ

After 400 days isolation

Janssen pause lifting Friday 23rd April

https://www.washingtonpost.com/health/2021/04/18/pause-johnson-johnson-coronavirus-vaccine-likely-be-lifted-by-friday-fauci-says/

Dr. Fauci

By Friday, we should have an answer as to where we’re going with it

I would think that we’re not going to go beyond Friday in the extension of this pause

I do think that there will likely be some sort of warning or restriction or risk assessment

I think it’ll likely say, ‘Okay, we’re going to use it, but be careful under these certain circumstances.’

The six cases of the blood clots were in women ages 18 and 48

Late summer or early fall (Dr. Fauci)

FDA and the CDC will probably decide on a third booster shot

Expects high school students will be vaccinated by the fall school term

Elementary schoolchildren will receive vaccine doses by the first quarter of 2022.

Now

Just over half of all adults in the US, at least one dose

131 million people

Sunday, 84 million, fully vaccinated

Anyone aged over 18 is now eligible

Dr. Fauci

US remains in a precarious position

US cases going up

https://covid.cdc.gov/covid-data-tracker/#trends_dailytrendscases

Source

The post Risk from India double mutation appeared first on Alternative.Media.

Cases, + 46,032 = 31,484,148

Deaths, + 255 (+ 4,881 – 7 days) = 566,292

Vaccinations

At least one dose, 133 million

Two doses, 86 million

Doses distributed, 264.5 million

Therefore, doses available, 44.4 million

US and India Serum Institute

Global supply chains

India

https://www.dw.com/en/india-covid-surge/a-57263667

B.1.617 seems to be outcompeting UK and Brazil variants

Levels of immune escape seem to be there

Early March, India’s Health Minister Harsh Vardhan

Country was in the endgame

of the Covid-19 pandemic.

K Srinath Reddy, Public Health Foundation of India

There was a feeling of triumphalism

Some felt we had achieved herd immunity.

Everyone wanted to get back to work.

This narrative fell on many receptive ears, and the few voices of caution were not heeded

Deaths, 180,000

Non-stop cremations

https://www.aljazeera.com/news/2021/4/20/non-stop-cremations-cast-doubt-on-indias-counting-of-covid-dead

Gujarat, Kamlesh Sailor (Crem manager)

We are working around the clock at 100 percent capacity to cremate bodies on time

Surat, Gujarat

Cremated more than 100 bodies a day over the last week

Surat, deaths in past week = 25

Ramnath Ghela Crematorium

Last month 20 per day

Now 80 per day

India, vaccinations

First dose, 127 million

3.5 million per day

70,000 vaccination centres

UK India variant

9th April

Bangladesh, Pakistan, both red listed

13th April

Bangladesh, had South Africa, not Brazil variant

Pakistan, had neither

India, had both

Now, 20th April

B.1.617, 103 UK cases, mostly linked to travel

Variant under investigation

Public Health England, 25 March and 7 April

3,345 arrivals from India

Of those 161 (4.8%) tested positive for Covid-19

https://www.bbc.co.uk/news/uk-56813025

https://www.bbc.co.uk/news/world-asia-india-56771766

https://static1.squarespace.com/static/5ef3652ab722df11fcb2ba5d/t/6076f57d3b43fb2db4a7c9c9/1618408831746/India+TF+Policy+Brief+April+2021.pdf

Prof Mark Walport, UK’s former chief scientific adviser

These decisions are almost inevitably taken a bit too late in truth, but what’s absolutely clear is that this variant is more transmissible in India

Becoming the dominant variant in India

so there’s good reasons for wanting to keep it out of the country if at all possible

From 04:00 BST on Friday 23 April

Most people who have travelled from or through India in the last 10 days will be refused entry

Others, Red listed

UK variants, official tracker

https://www.gov.uk/government/publications/covid-19-variants-genomically-confirmed-case-numbers/variants-distribution-of-cases-data

ONS

https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronaviruscovid19roundup/2020-03-26

Prevalence

The percentage of people testing positive for the coronavirus has decreased in all four UK countries

Up to 10 April 2021

England

112,600 people (0.21%) in the community

(3rd April, 161,900)

1 in 480 people

Wales

3,300 people (0.11%)

(3rd April, 3,800)

1 in 920 people

Northern Ireland

2,600 people (0.14%)

(3rd April, 6,100)

1 in 710 people

Scotland

10,500 people (0.20%)

(3rd April, 13,000)

1 in 500 people

UK, now

https://coronavirus.data.gov.uk

Source

The post High death numbers in India appeared first on Alternative.Media.

https://www.bbc.co.uk/news/health-56849874

45-49 at 59% so far

Care home staff, 80%

Proportion of over 18s vaccinated in UK

https://coronavirus.data.gov.uk

Patients in hospital

2% of hospital beds

Zoe latest

https://covid.joinzoe.com/data#levels-over-time

NE highest

SW lowest

No big surges in South London (SA variant)

No data on India variant yet

Chance of contracting CoViD in next 24 hours

No vaccine 1 in 46,000

12 days after first dose 1 in 74,000

12 days after 2nd dose 1 in 114,000

Lancet paper next week

People in care homes with two vaccines should be given more freedoms

E mail from CDC to CNN, Breakthrough infections

https://www.medscape.com/viewarticle/949381?src=wnl_edit_tpal&uac=127834AR&impID=3316056&faf=1

https://edition.cnn.com/2021/04/14/health/breakthrough-infections-covid-vaccines-cdc/index.html

Vaccinated people who become infected, 1 in 13,275

Of these, asymptomatic 29%

Required hospitalization 1 in 194,444

Deaths 1 in 1,040,540

US

Vaccine tipping point?

Point where supply outstrips demand

This week, 3 million per day

Last week, 3.3 million per day

Summertime, hopes life will return to normal

India

https://www.bbc.co.uk/news/world-asia-india-56826645

Highest ever one day total anywhere

Cases, + 314,835 = 16 million

(US, 8th Jan, + 313,000)

30% positivity rates

Deaths, 2,104 = 185,000

Crowds outside hospitals

People dying waiting for admission

Oxygen supply variable

Deputy Delhi Chief Minister, Manish Sisodia

Some hospitals have run out of oxygen

Delhi crematorium resorting to building pyres in its car park

Specific example

Nashik, Western India

https://www.washingtonpost.com/world/2021/04/21/india-hospital-oxygen-deaths/

Broken valve on oxygen tank

150 CoViD patients

22 died

Prime Minister Narendra Modi

Asked officials to find ways to produce more oxygen

States to come down heavily on anyone hoarding supplies

Curfew in Delhi, increased restrictions in Maharashtra

Vaccines, 130 million so far

Evidence going back more than 30 years suggests that platelets can biosynthesize proteins

https://www.tandfonline.com/doi/abs/10.1080/09537100801990582?journalCode=iplt20

Sweden

https://www.dw.com/en/do-swedens-covid-liberties-cost-lives/a-57268022

Size limitations on public gatherings

8 p.m. closing time for restaurants and pubs

Other, recommendations

January, passengers on public transportation encouraged to face cover

South Africa

31 million doses of the J&J

30 million doses of Pfizer BioNTech

https://www.washingtonpost.com/nation/2021/04/22/coronavirus-covid-live-updates-us/

Resume using the Johnson & Johnson vaccine

South Africa, no reports of unusual blood clots

290,000 of 1.2 million health workers have been given the J&J vaccine in a study

Source

The post Unnecessary deaths in India appeared first on Alternative.Media.