If the pharmaceutical industry,
(Dr Michael Holick)
had developed a single drug capable of:
Reducing cancer mortality by more than 25%
Reducing the incidence of metastatic and fatal cancer by 38%
Reducing autoimmune disorders by 39%
Reducing type 1 diabetes by 88%
Preventing advancement of prediabetes to type 2 diabetes by 76%
Reducing peripheral vascular disease by 80%
Lowering risk of upper respiratory tract infections by 58%
Reducing covid infectivity by 54%
Reducing COVID 19 infection by up to 74%
Reducing covid RDS by 78%
Reducing COVID 19 hospitalizations by up to 22%
Reducing COVID 19 mortality by up to 45 – 66%
Accelerating COVID positive patients to COVID negativity by 66%
Reducing risk of preterm birth by 62%
Reducing risk of pre-eclampsia by more than 50%
Reducing gestational diabetes, 50%
Reducing infant dental caries, 75%
Reducing multiple sclerosis, 62%
Colon cancer, 80%
Cardiovascular mortality, 67%
Autoimmune disease, 39%
the drug would be heralded as a “miracle drug.”
With patent protection, this single drug sold worldwide would be the first trillion-dollar drug.
The sunshine vitamin D provides all these health benefits especially when an adequate amount is taken to sustain circulating concentrations of 25(OH)D of at least 30 ng/ mL, (75 nm / L)
with the maximum benefit obtained with concentrations of 40- 60 ng/mL,(100 – 150 nm / L)
At least 30 ng/ mL
Best, 40- 60 ng/mL.
GDP (Guideline Development Panel, US Endocrine Society)
24% or more (children and adults),
United States, have a circulating concentration of 25(OH)D less than 20 ng/mL.
Approximately 40% in Europe have a circulating concentration of 25(OH)D less than 20 ng/mL.
Recent report from the VITAL trail
https://www.bmj.com/content/376/bmj-2021-066452
For the last 3 years of the intervention
Group receiving 2000 IUs vitamin D3 daily raised their serum concentration of 25(OH)D from 29.8 ng/mL to 41.8 ng/mL after 1 year
This group had 39% fewer confirmed autoimmune diseases than the placebo group (who were permitted to take up to 800 IUs daily)
NIH, 5 – 8% in US have an autoimmune condition.
When should I suspect or test for vitamin D deficiency?
https://cks.nice.org.uk/topics/vitamin-d-deficiency-in-adults/diagnosis/diagnosis/
Do not routinely test for vitamin D deficiency in people who are asymptomatic.
Source