• Wed. May 22nd, 2024

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Risks following infection versus vaccination

Bywebmaster

May 20, 2024



UK, (England), Risk of thrombocytopenia and thromboembolism after covid-19 vaccination and SARS-CoV-2 positive testing: self-controlled case series study

https://www.bmj.com/content/374/bmj.n1931

https://www.bbc.co.uk/news/health-58347434

Prof Julia Hippisley-Cox

People vaccinated with first doses, 16 or over

N = 29,121,633

Oxford-AstraZeneca (ChAdOx1 nCoV-19)

N = 19,608,008

Pfizer-BioNTech (BNT162b2mRNA)

N = 9,513,625

People testing positive SARSCoV-2

N = 1,758,095

Within 28 days of three exposures

First dose of the ChAdOx1 nCoV-19 vaccine

First dose of the BNT162b2 mRNA vaccine

SARS-CoV-2 positive test

For every 10 million people vaccinated with the AstraZeneca

An extra 107 would be hospitalised or die from thrombocytopenia

(1 in 93,459)

9 times lower than the risk following an infection

An extra 66 would be hospitalised or die from blood clots in the veins

Nearly 200 times lower than the risk following an infection

For every 10 million people vaccinated with the Pfizer

An extra 143 extra strokes would be seen

(1 in 69,930)

12 times lower than the risk following an infection

Myocarditis and pericarditis

Chest pain, shortness of breath, or feelings of having a fast-beating, fluttering, or pounding heart

https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-june-25-2021

https://www.cdc.gov/mmwr/volumes/70/wr/mm7027e2.htm

52 million doses to 12–29 years

1,226 reports of myocarditis after mRNA vaccination 42,414

One in 42,414

Data demonstrate increased risks, particularly within the seven days following the second dose

The observed risk is higher among males under 40 years of age compared to females and older males

Risk is highest in males 12 through 17 years of age

Source

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