Vary greatly on the two sides of the pond. US goes one way, the UK another.
UK, awaiting rule change for 2 dosers
https://www.bbc.co.uk/news/health-56929483
Indoor gatherings
Wales, 3rd May
England, Scotland 17th May
NI, 24th May
Prof Jonathan Van-Tam
If two people who both had two doses of vaccine,
and have both served at least 14 days after their second dose,
then I would be highly confident scientifically that if they were reputable vaccines then
indeed it would be incredibly safe for those two people to meet
Paul Hunter, Professor of Medicine, University of East Anglia
True just now with B117
The issue is variants with escape mutations that are less affected by the vaccine,
and we haven’t come to clear understanding of what those risks are
UK, Indian or South African variants yet to make an impact
https://covid.joinzoe.com/post/indian-or-south-african-variants-yet-to-make-an-impact
22nd April
India
https://www.aljazeera.com/news/2021/5/1/fire-in-hospitals-intensive-care-kills-18-in-indias-gujarat
https://www.washingtonpost.com/nation/2021/04/29/coronavirus-covid-live-updates-us/
Cases, + 379,257 + 386,452 + 401,993 = 19,100,000
Deaths, + 3,645 + 3,523 = 211,853
Vaccinations
All adults now eligible
Was over 45s
One dose, 10%
Two doses 1.5%
India / Australia
Criminal offence for citizens to return home, from Monday
India / US
Restrictions from 4th May
Most non-US citizens, India within the last 14 days will not be allowed into US
India / France
First case was detected in Lot-et Garonne, in southwestern France
The patient is currently hospitalised in Bordeaux
https://www.lexpress.fr/actualite/societe/sante/ce-que-l-on-sait-des-differents-cas-de-variants-indiens-detectes-en-france_2149875.html
Two more cases in the south east – in the Marseille département of Bouches-du-Rhône.
Two people returning from India without any link to one another
10-day quarantine for arrivals from India, Brazil, South Africa, Chile and Argentina
https://www.thelocal.fr/20210430/three-cases-of-the-indian-variant-of-covid-detected-in-france/?utm_source=piano&utm_medium=email&utm_campaign=213&tpcc=newsletter_members&pnespid=1fBz_aVRDRWNUoF70GTcVJXtQlLxVSWUNbDvEHY
Sequencing rate
https://www.washingtonpost.com/nation/2021/04/29/coronavirus-covid-live-updates-us/#link-UVLBM3S2DFH65KGAD5772HMJ6Q
Iceland, 78.8%
Australia, 60.3%
New Zealand, 48.5%
Denmark, 20.2%
Taiwan, 16%
UK, 8.7%
Norway, 5.6%
Vietnam, 5.5%
US, 1%
India (102) 18,000,000 (10,626) 0.06%
U.S. government, $100 million worth of supplies
US State Department, U.S. citizens to leave India as soon as it is safe to do
https://in.usembassy.gov/health-alert/
Spread from cities to small towns
https://www.bbc.co.uk/news/world-asia-india-56913047
Spread now occurring, but underreported
Corruption and black markets
Medical debt already a big problem in India
Remdesivir problem
https://bnf.nice.org.uk/medicinal-forms/remdesivir.html
Remdesivir for the Treatment of Covid-19 — Final Report (NEJM, 5th November 2020)
https://www.nejm.org/doi/full/10.1056/nejmoa2007764
Double-blind, randomized, placebo-controlled trial of intravenous remdesivir
Ten day course
Hospitalized with Covid-19 with evidence of lower respiratory tract infection
N = 1062
Remdesivir group, 541
Placebo, 521
Remdesivir group, n = 541
Median recovery time, 10 days
Need for oxygen, 13 days
Mortality by day 15 was 6.7%
Mortality by day 29 was 11.4%
Placebo controls, n = 521
Median recovery time 15 days
Need for oxygen, 21 days
Mortality by day 15 was 11.9%
Mortality by day 29 was 15.2% (HR = 0.73)
Serious adverse events
Remdesivir group, 24.6%
Placebo group, 31.6%
Serious adverse events in placebo group, 31.6%
Source