• Fri. Nov 8th, 2024

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US pause Janssen vaccine

Bywebmaster

Sep 5, 2024



Joint CDC and FDA Statement on Johnson & Johnson COVID-19 Vaccine

https://www.cdc.gov/media/releases/2021/s0413-JJ-vaccine.html

https://www.washingtonpost.com/health/2021/04/13/johnson-and-johnson-vaccine-blood-clots/

Cerebral venous sinus thrombosis, together with low platelets

Some sort of immune response

6 cases from 6.8 million doses

Look out for, severe headache, abdominal pain, leg pain or shortness of breath within three weeks of vaccination

Paul A.Offit, vaccine specialist, Children’s Hospital of Philadelphia

I think it’s the prudent thing to do

I think it’s real — this is a rare, but real association

Advisory Committee on Immunization Practices (ACIP), meets today

EMA also investigating, delaying European rollout

Janet Woodcock, acting commissioner, Food and Drug Administration

One reason for the pause, health professionals must know not to use heparin

All six cases in the US, occurred among women, 18 to 48

6 – 13 days after vaccination

Of the 6, 1 death and 1 critical

Of the 6, 2 discharged

The person in critical condition was (reportedly) treated with heparin

Peter Marks, director of the FDA’s centre for biologics evaluation and research

hesitate to call it a class effect related to adenovirus vector vaccines

It’s plainly obvious to us already that what we’re seeing with the Jansen vaccines looks very similar to what is being seen with the AstraZeneca vaccine

AstraZeneca, chimpanzee adenoviral vector

Janssen, human adenoviral vector vaccine

I can’t make some broad statement yet, but obviously they are from the same general class of viral vectors

Scale of the problem

100 million doses to US end of May

can produce 1 billion doses globally by the end of the year

has agreed to sell 500 million doses to developing nations via Covax purchasing agreement

agreed to sell up to 400 million to African countries

Turkey

https://www.telegraph.co.uk/global-health/science-and-disease/coronavirus-news-lockdown-pubs-restaurants-shops-cases-deaths/

Cases, + 59,187 = 3,962,000 million

Deaths, + 273 = 34,455

President Tayyip Erdogan, partial closures

Ramadan started yesterday

France

Cases, + 39,113 = 5,100,000

Deaths, + 324 (in hospital) = 99,480

ITU = 5,952

One month lockdown in place since the end of March

France will suspend all flights to and from Brazil

Sweden

AZ, being given to over 65s

J&J arriving this week

Russia

Manufacturing of Sputnik V, soon in India, (50 m per month) Serbia, Iran, Italy

India

India approved Sputnik V on Monday

UK

https://www.telegraph.co.uk/global-health/science-and-disease/lockdown-eases-worried-should-londons-cluster-south-african/

Surge PCR testing south London

Lambeth and Wandsworth (population 656,000)

Testing available for all, symptomatic or asymptomatic

Live, work or travel through

South Africa variant

Eeek, E484K, seems to reduce AZ efficacy

Still protects against severe disease

Does not seem to out compete UK variant

New formulation of AZ for third shot later this year

Who are these guys?

Vitamin D

https://vdmeta.com

Source

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