US deaths more than 1918 pandemic
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https://www.cdc.gov/flu/pandemic-resources/1918-pandemic-h1n1.html
H1N1 virus with genes of avian origin
United States, first identified in military in spring 1918
One-third of the world’s population became infected
Global deaths, at least 50 million
US deaths, 675,000
(CDC, 2021, 666,440)
(JH, 2021, 681,199)
https://coronavirus.jhu.edu/map.html
(population, x 3 today)
Pandemic subsides, but (H1N1) continues to circulate seasonally for 38 years
https://www.cdc.gov/flu/pandemic-resources/1918-commemoration/milestone-infographic.htm
Mortality in 1918 / 1919
High in people younger than 5 years old
20-40 years old, and 65 years and older
No vaccine, no antibiotics
UK in 1918
https://www.historic-uk.com/HistoryUK/HistoryofBritain/The-Spanish-Flu-pandemic-of-1918/
Deaths, 228,000
(2021, 135,621 to 158,664)
Global infection fatality rate, 10% to 20%
Mr Biden
Extra 500 million Pfizer doses for poorer countries
The Food and Drug Administration
https://www.washingtonpost.com/health/2021/09/22/pfizer-booster-shot-fda-authorizes/
Authorized a Pfizer booster, 65 and older
People 18 through 64, at high risk of severe illness
frequent institutional or occupational exposure
Six months
Issuing emergency clearance
FDA commissioner Janet Woodcock
health care workers, teachers and day care staff, grocery workers, homeless shelters or prisons
Centers for Disease Control and Prevention still must make precise recommendations
Key goal of boosters, prevention of serious disease, not prevention of mild infection
? Pfizer booster for people who have been vaccinated with the Moderna or Johnson & Johnson
Fewer side effects after third dose of mRNA vaccines compared with the second dose
https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2021-09-22/07-COVID-Talbot-508.pdf
COVID-19 Vaccine Safety Technical (VaST) Work Group
Assessment of 3rd dose safety data
H. Keipp Talbot, MD MPH (VaST Chair) Robert H. Hopkins, Jr., MD (NVAC Chair)
Israel
3rd doses ,~2.8 M
≥12 years
Most to persons ≥60 years
Rates of reported systemic, local, neurologic, allergic, and other reactions were substantially lower after dose 3 than after dose 1 or 2
1,328 non serious
19 serious adverse events, (7 possibly associated with vaccination)
https://www.who-umc.org/vigibase/vigibase/
http://www.vigiaccess.org
Correction
https://www.hindustantimes.com/cities/lucknow-news/yogi-adityanath-launches-covid-19-medical-kits-for-covid-19-symptomatic-children-101623747649057.html
State government, 50 lakh medical kits through village surveillance committees
Source